Caenorhabditis elegans (C. elegans) or round worms are small worms with 60% genetic homology to humans. They are transparent which enables facile visualization by optical microscopy and they exhibit short life span and fast reproduction cycle facilitating the evaluation in the whole life cycle.
Use of C. elegans as animal models surpasses the complex process of obtaining ethical animal rights, provide us with a large sample size (around 1000 worms per group!), and can be used even in a chemical synthesis laboratory for safe-by-design approach to design novel nanomaterials! C. elegans for nanotechnology is witnessing a rising research interest and our group works in toxicity evaluation through oral administration of nanomaterials such as iron oxide NPs, gold NPs, polypyrrole NPs and bacterial nanocellulose.
The workshop will include a short introductory presentation showing the advantages, state of the art, future avenues and challenges. Later, the participants will be trained with "video-demo" handle the worms and carry out some maintanence and growth experiments as well as some interesting photos and videos of the worm world and nanoworld will be shown to the audience.